
 PEG PRODUCTS 
			

 PEGylation Chemistry Info		
 
		PEGylation Chemistry Info
		
			
			
				
				
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Example 1 :
						
							PEG-epoxide pegylates hydroxyl groups at a mild reactivity and is most effectively coupled at higher pH(8.5-9.5).
							
The PEG-epoxide may also pegylate hydoxyl, amine, thiol groups. The PEG-epoxide shows excellent water stability at
							basic pH.
							
						 
					 
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Example 2 :
						
							PEG-NPC also pegylates hydroxyl groups
							
						 
					 
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Example 3 :
						
							PEG-isocyanate also pegylates hydroxyl groups yielding stable urethane linkage. However, its reactivity may be best exploited for pegylating non-peptide moieties such as drugs, hydroxyl-containing matrices for chromatography, and also to produce biocompatible surfaces.